|
KMID : 0861020180330020001
|
|
Korea Journal of Herbology
2018 Volume.33 No. 2 p.1 ~ p.7
|
|
|
Research for Reduction of Body Fat and Development of High Functionality in Young Persimmon Fruit
|
|
Kim Soo-Hyun
Lee Ah-Reum
Kim Kyeong-Jo
Kim Il-Gyu
Rhee Man-Hee
Kim Hyun-Kyoung
Roh Seong-Soo
|
|
|
Abstract
|
|
|
Objectives : This study was conducted to evaluate the antioxidant activity and inhibitory activity of pancreatic lipase in vitro using natural products sangju dungsi, chungdo bansi, kabju baekmok three kind of young persimmon fruit extracts and to develop a high - functional anti - obesity substance with reduced body fat.
Methods : The antioxidative effect of the three kind of young persimmon fruit extracts was determined by hot water extraction, 30% EtOH extraction and 70% EtOH extraction. The antioxidant activities were evaluated through radical scavenging assays using 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2’-azino-bis (3-ethylbenzothiazoline-6- sulphonic acid) (ABTS) radicals. Furthermore, we examined total phenol and flavonoids contents. And the pancreatic lipase inhibition was measured by selecting the sangju dungsi extract with antioxidant effect.
Results : The yield of water, 30% and 70% EtOH extract from young persimmon fruit was sangju dungsi (water 8.3%, 30% EtOH 18.1%, 70% EtOH 16.9%), chungdo bansi (water 16.2%, 30% EtOH 16.1%, 70% EtOH 11.6%), kabju baekmok (water 16%, 30% EtOH 16.8%, 70% EtOH 11.5%). The sangju dungsi 30% EtOH extract eminent DPPH (IC50, 19.25 ± 2.94 ㎍/㎖) and ABTS (IC50, 19.94 ± 4.07 ㎍/㎖) radical scavenging activity, and total phenol 52.37 ± 0.78 ㎎/g and flavonoid 7.97 ± 0.13 ㎎/g contents were also excellent. It also showed excellent pancreatic lipase inhibition efficacy.
Conclusion : The extracts from the three kind of young persimmon fruit extracts showed excellent antioxidant activity. sangju dungsi 30% EtOH extract may be a new anti-obesity material by reducing fat absorption through the inhibition of pancreatic lipase.
|
|
|
KEYWORD
|
|
|
young persimmon fruit, anti-oxidant, anti-obesity, pancreatic lipase
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
|
|